Is Bigger Really Badder?
نویسنده
چکیده
Increasing attention is being focused on the role(s) that obesity may play in the development of cardiovascular disease, particularly congestive heart failure (CHF).1,2 Several indirect or associated effects are potential culprits. For example, obesity is strongly associated with many atherosclerotic risk factors, including arterial hypertension, insulin resistance, diabetes, and dyslipidemia.3 Therefore, it is not surprising that obese people tend to have premature and accelerated coronary artery disease, a common precursor of CHF.4,5 In addition to promoting coronary heart disease, obesity has been associated with atrial fibrillation, another condition that can contribute to CHF.6 Lastly, obesity often adversely impacts right heart function via the ill effects of sleep disordered breathing or restrictive lung disease.7 The aforementioned factors may individually or collectively produce a clinical syndrome of CHF in patients who are obese.
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